Study finds how lung cancer mutations may influence treatment response
Why are some lung cancers more difficult to treat than others? A team of researchers may have found a new clue. A recent study found that two specific genetic mutations influence cancerous cells and make them more likely to resist treatment. The mutations concern the genes EGFR, which is involved in cell growth, and TP53, which helps regulate cell division and prevent tumours. Mutations in these proteins are often hallmarks of cancer which is why the team of researchers from the University College London (UCL), the UK-based Francis Crick Institute and AstraZeneca investigated them using mouse ...